Hua Wu Selected Research

Integrins

6/2023	Stevioside protects primary articular chondrocytes against IL-1β-induced inflammation and catabolism by targeting integrin.
1/2022	Dual Targeting of Integrin αvβ3 and Neuropilin-1 Receptors Improves Micropositron Emission Tomography Imaging of Breast Cancer.
10/2020	Targeted Radionuclide Therapy in Patient-Derived Xenografts Using 177Lu-EB-RGD.
1/2020	Syntheses and Preliminary Evaluation of Dual Target PET Probe [18F]-NOTA-Gly3- E (2PEG4-RGD-WH701) for PET Imaging of Breast Cancer.
1/2019	Integrin αvβ3-targeted radionuclide therapy combined with immune checkpoint blockade immunotherapy synergistically enhances anti-tumor efficacy.
1/2017	Novel "Add-On" Molecule Based on Evans Blue Confers Superior Pharmacokinetics and Transforms Drugs to Theranostic Agents.
1/2016	Simultaneous SPECT imaging of multi-targets to assist in identifying hepatic lesions.
12/2014	Imaging integrin αvβ 3 and NRP-1 positive gliomas with a novel fluorine-18 labeled RGD-ATWLPPR heterodimeric peptide probe.
7/2013	Imaging integrin α(v)β(3) positive glioma with a novel RGD dimer probe and the impact of antiangiogenic agent (Endostar) on its tumor uptake.

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Hua Wu Research Topics

Disease

99	Neoplasms (Cancer) 06/2024 - 01/2006
38	Infections 10/2023 - 10/2007
33	Neoplasm Metastasis (Metastasis) 06/2024 - 07/2005
24	Inflammation (Inflammations) 06/2024 - 10/2014
15	Hepatocellular Carcinoma (Hepatoma) 03/2024 - 02/2008
12	Carcinogenesis 01/2024 - 11/2014
11	Breast Neoplasms (Breast Cancer) 09/2022 - 06/2004
11	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 11/2014
9	Lung Neoplasms (Lung Cancer) 11/2023 - 10/2012
9	Liver Neoplasms (Liver Cancer) 10/2023 - 01/2006
9	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 08/2005
8	Esophageal Neoplasms (Esophageal Cancer) 11/2023 - 04/2009
8	Osteosarcoma (Osteogenic Sarcoma) 02/2023 - 05/2011
7	Diarrhea 08/2022 - 04/2014
7	Nasopharyngeal Carcinoma 01/2022 - 07/2005
6	Rheumatoid Arthritis 04/2024 - 12/2010
6	Carcinoma (Carcinomatosis) 04/2018 - 01/2004
5	Osteoarthritis 04/2024 - 01/2021
5	Stomach Neoplasms (Stomach Cancer) 10/2023 - 09/2011
5	COVID-19 05/2022 - 01/2020
5	Hypoxia (Hypoxemia) 04/2019 - 11/2014
4	Colitis 05/2024 - 02/2016
4	Ulcer 04/2024 - 09/2017
4	Pancreatic Neoplasms (Pancreatic Cancer) 10/2023 - 08/2009
4	Asthma (Bronchial Asthma) 05/2023 - 09/2005
4	Fibrosis (Cirrhosis) 01/2023 - 01/2016
4	Lymphatic Metastasis 01/2023 - 02/2019
4	Osteoporosis 12/2022 - 10/2014
4	Adenocarcinoma of Lung 01/2020 - 12/2012
3	Thyroid Neoplasms (Thyroid Cancer) 12/2023 - 01/2022
3	Body Weight (Weight, Body) 11/2023 - 01/2006
3	Obesity 11/2023 - 01/2007
3	Diabetes Mellitus 04/2023 - 01/2018
3	Fever (Fevers) 04/2023 - 06/2011
3	Diabetic Foot 02/2023 - 09/2017
3	Esophageal Squamous Cell Carcinoma 01/2023 - 04/2014
3	Vesicular Stomatitis 01/2022 - 10/2007
3	Lung Injury 01/2022 - 02/2019
3	Peritoneal Neoplasms 01/2021 - 12/2007
3	Human Influenza (Influenza) 10/2020 - 06/2011
3	Adenocarcinoma 01/2020 - 09/2014
3	Squamous Cell Carcinoma of Head and Neck 02/2019 - 01/2014
3	Sepsis (Septicemia) 01/2019 - 01/2016
3	Porcine Reproductive and Respiratory Syndrome (PRRS) 04/2018 - 05/2012
3	Liver Cirrhosis (Hepatic Cirrhosis) 01/2018 - 01/2016
3	Anemia 01/2015 - 10/2004
3	Glioma (Gliomas) 12/2014 - 05/2013

Drug/Important Bio-Agent (IBA)

45	Proteins (Proteins, Gene)FDA Link 06/2024 - 02/2004
21	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2024 - 10/2007
13	Peptides (Polypeptides)IBA 01/2024 - 06/2008
10	Anti-Bacterial Agents (Antibiotics)IBA 05/2023 - 01/2017
10	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 10/2022 - 11/2014
9	IntegrinsIBA 06/2023 - 07/2013
9	VaccinesIBA 05/2023 - 05/2012
9	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2018
8	CytokinesIBA 01/2022 - 08/2011
7	1,4,7- triazacyclononane- N,N',N''- triacetic acid (NOTA)IBA 01/2020 - 11/2014
6	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 10/2004
6	AntibodiesIBA 05/2023 - 01/2016
6	Neutralizing AntibodiesIBA 10/2020 - 02/2011
6	Small Interfering RNA (siRNA)IBA 01/2020 - 12/2012
6	ErbB Receptors (EGF Receptor)IBA 01/2017 - 12/2007
5	Radioisotopes (Radionuclides)IBA 05/2024 - 01/2019
5	Therapeutic UsesIBA 04/2024 - 01/2006
5	Interleukin-6 (Interleukin 6)IBA 04/2024 - 02/2019
5	RNA (Ribonucleic Acid)IBA 11/2023 - 04/2018
5	TNF Receptor-Associated Factor 6 (TRAF6)IBA 01/2022 - 01/2016
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 01/2006
5	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2017 - 03/2010
4	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2024 - 07/2015
4	68Ga-FAPIIBA 01/2024 - 01/2021
4	FAPI-46IBA 01/2024 - 10/2022
4	RadiopharmaceuticalsIBA 12/2023 - 12/2014
4	Monoclonal AntibodiesIBA 07/2021 - 01/2006
4	Messenger RNA (mRNA)IBA 03/2021 - 03/2015
4	Tyrosine Kinase InhibitorsIBA 02/2021 - 07/2015
4	Immunoglobulin G (IgG)IBA 01/2020 - 01/2013
4	Cadherins (E-Cadherin)IBA 10/2016 - 11/2014
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 06/2024 - 03/2010
3	Volatile Oils (Essential Oils)IBA 05/2024 - 10/2021
3	Glucose (Dextrose)FDA LinkGeneric 02/2023 - 05/2007
3	Matrix Metalloproteinases (MMPs)IBA 02/2023 - 11/2014
3	CollagenIBA 01/2023 - 01/2018
3	AntigensIBA 09/2022 - 09/2014
3	Estrogen ReceptorsIBA 01/2022 - 01/2017
3	Immunoglobulins (Immunoglobulin)IBA 01/2022 - 11/2014
3	2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate (AITC)IBA 11/2021 - 04/2017
3	Imipenem FDA Link 01/2021 - 11/2019
3	Immunoglobulin E (IgE)IBA 01/2021 - 01/2012
3	Evans Blue (Blue, Evans)FDA Link 01/2020 - 01/2006
3	CateninsIBA 01/2019 - 01/2011
3	Proliferating Cell Nuclear Antigen (PCNA)IBA 12/2014 - 08/2002

Therapy/Procedure

60	Therapeutics 06/2024 - 06/2008
16	Radiotherapy 08/2022 - 08/2005
9	Drug Therapy (Chemotherapy) 07/2023 - 07/2005
6	Chemoradiotherapy 01/2023 - 01/2014
4	Precision Medicine 06/2024 - 01/2017
4	Length of Stay 08/2021 - 04/2012
3	Immunotherapy 09/2022 - 01/2019
3	Aftercare (After-Treatment) 01/2017 - 10/2009